The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress

Humanin (HN) is a hydrophobic 24-amino acid peptide derived from mitochondrial DNA that modulates cellular responses to oxidative stress and protects human retinal pigment epithelium (RPE) cells from apoptosis. To solubilize HN, this report describes two genetically-encoded fusions between HN and el...

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Dades bibliogràfiques
Publicat a:Nanomedicine
Autors principals: Li, Zhe, Sreekumar, Parameswaran G., Peddi, Santosh, Hinton, David R., Kannan, Ram, MacKay, J. Andrew
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263384/
https://ncbi.nlm.nih.gov/pubmed/31655204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102111
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