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Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration

The mitochondrial-derived peptides (MDPs) are a new class of small open reading frame encoded polypeptides with pleiotropic properties. The prominent members are Humanin (HN) and small HN-like peptide (SHLP) 2, which encode 16S rRNA, while mitochondrial open reading frame of the twelve S c (MOTS-c)...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Sreekumar, Parameswaran G., Kannan, Ram
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767738/
https://ncbi.nlm.nih.gov/pubmed/32768357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101663
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