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The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress

Humanin (HN) is a hydrophobic 24-amino acid peptide derived from mitochondrial DNA that modulates cellular responses to oxidative stress and protects human retinal pigment epithelium (RPE) cells from apoptosis. To solubilize HN, this report describes two genetically-encoded fusions between HN and el...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Li, Zhe, Sreekumar, Parameswaran G., Peddi, Santosh, Hinton, David R., Kannan, Ram, MacKay, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263384/
https://ncbi.nlm.nih.gov/pubmed/31655204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102111
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