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The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress

Humanin (HN) is a hydrophobic 24-amino acid peptide derived from mitochondrial DNA that modulates cellular responses to oxidative stress and protects human retinal pigment epithelium (RPE) cells from apoptosis. To solubilize HN, this report describes two genetically-encoded fusions between HN and el...

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Dettagli Bibliografici
Pubblicato in:Nanomedicine
Autori principali: Li, Zhe, Sreekumar, Parameswaran G., Peddi, Santosh, Hinton, David R., Kannan, Ram, MacKay, J. Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263384/
https://ncbi.nlm.nih.gov/pubmed/31655204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102111
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