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Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration

Ceramide and its metabolic derivatives are important modulators of cellular apoptosis and proliferation. Dysregulation or imbalance of their metabolic pathways may promote the development of retinal degeneration. The aim of this study was to identify the expression and regulation of key enzymes of t...

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Autori principali: Zhu, DanHong, Sreekumar, Parameswaran G., Hinton, David R., Kannan, Ram
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840213/
https://ncbi.nlm.nih.gov/pubmed/19765607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2009.09.002
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