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Effect of Adjuvant Release Rate on the Immunogenicity of Nanoparticle-Based Vaccines: A Case Study with a Nanoparticle-Based Nicotine Vaccine

Adjuvants are a critical component for vaccines, especially for a poorly immunogenic antigen, such as nicotine. However, the impact of adjuvant release rate from a vaccine formulation on its immunogenicity has not been well illustrated. In this study, we fabricated a series of hybrid-nanoparticle-ba...

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Библиографические подробности
Опубликовано в: :Mol Pharm
Главные авторы: Zhao, Zongmin, Hu, Yun, Harmon, Theresa, Pentel, Paul, Ehrich, Marion, Zhang, Chenming
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263372/
https://ncbi.nlm.nih.gov/pubmed/31075204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00279
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