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4E-T-bound mRNAs are stored in a silenced and deadenylated form
Human 4E-T is an eIF4E-binding protein (4E-BP) present in processing (P)-bodies that represses translation and regulates decay of mRNAs destabilized by AU-rich elements and microRNAs (miRNAs). However, the underlying regulatory mechanisms are still unclear. Here, we show that upon mRNA binding 4E-T...
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| 出版年: | Genes Dev |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7263148/ https://ncbi.nlm.nih.gov/pubmed/32354837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.336073.119 |
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