Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing

A key player in translation initiation is eIF4E, the mRNA 5′ cap-binding protein. 4E-Transporter (4E-T) is a recently characterized eIF4E-binding protein, which regulates specific mRNAs in several developmental model systems. Here, we first investigated the role of its enrichment in P-bodies and eIF...

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Bibliografske podrobnosti
Main Authors: Kamenska, Anastasiia, Lu, Wei-Ting, Kubacka, Dorota, Broomhead, Helen, Minshall, Nicola, Bushell, Martin, Standart, Nancy
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950672/
https://ncbi.nlm.nih.gov/pubmed/24335285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1265
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