Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor

Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it is taken up by renal cells and the vesicles release their...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Autores principales: Johansson, Karl, Willysson, Annie, Kristoffersson, Ann-Charlotte, Tontanahal, Ashmita, Gillet, Daniel, Ståhl, Anne-lie, Karpman, Diana
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261856/
https://ncbi.nlm.nih.gov/pubmed/32523894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00212
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