Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism

Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC), that cause gastrointestinal infection leading to hemolytic uremic syndrome. The aim of this study was to investigate if Stx signals via ATP and if blockade of purinergic receptors could be protective. Stx in...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Johansson, Karl E., Ståhl, Anne-Lie, Arvidsson, Ida, Loos, Sebastian, Tontanahal, Ashmita, Rebetz, Johan, Chromek, Milan, Kristoffersson, Ann-Charlotte, Johannes, Ludger, Karpman, Diana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779916/
https://ncbi.nlm.nih.gov/pubmed/31591425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50692-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky