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Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism
Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC), that cause gastrointestinal infection leading to hemolytic uremic syndrome. The aim of this study was to investigate if Stx signals via ATP and if blockade of purinergic receptors could be protective. Stx in...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6779916/ https://ncbi.nlm.nih.gov/pubmed/31591425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50692-1 |
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