Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism

Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC), that cause gastrointestinal infection leading to hemolytic uremic syndrome. The aim of this study was to investigate if Stx signals via ATP and if blockade of purinergic receptors could be protective. Stx in...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Johansson, Karl E., Ståhl, Anne-Lie, Arvidsson, Ida, Loos, Sebastian, Tontanahal, Ashmita, Rebetz, Johan, Chromek, Milan, Kristoffersson, Ann-Charlotte, Johannes, Ludger, Karpman, Diana
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779916/
https://ncbi.nlm.nih.gov/pubmed/31591425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50692-1
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki