A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles

Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli, which are non-invasive strains that can lead to hemolytic uremic syndrome (HUS), associated with renal failure and death. Although bacteremia does not occur, bacterial virulence factors gain access to the circulati...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Ståhl, Anne-lie, Arvidsson, Ida, Johansson, Karl E., Chromek, Milan, Rebetz, Johan, Loos, Sebastian, Kristoffersson, Ann-Charlotte, Békássy, Zivile D., Mörgelin, Matthias, Karpman, Diana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342247/
https://ncbi.nlm.nih.gov/pubmed/25719452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004619
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