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Shiga Toxin Uptake and Sequestration in Extracellular Vesicles Is Mediated by Its B-Subunit

Shiga toxin (Stx)-stimulated blood cells shed extracellular vesicles (EVs) which can transfer the toxin to the kidneys and lead to hemolytic uremic syndrome. The toxin can be taken up by renal cells within EVs wherein the toxin is released, ultimately leading to cell death. The mechanism by which St...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Toxins (Basel)
Asıl Yazarlar: Willysson, Annie, Ståhl, Anne-lie, Gillet, Daniel, Barbier, Julien, Cintrat, Jean-Christophe, Chambon, Valérie, Billet, Anne, Johannes, Ludger, Karpman, Diana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404996/
https://ncbi.nlm.nih.gov/pubmed/32664382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12070449
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