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Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions

Germline variations in immunoglobulin genes influence the repertoire of B cell receptors and antibodies, and such polymorphisms may impact disease susceptibility. However, the knowledge of the genomic variation of the immunoglobulin loci is scarce. Here, we report 25 potential novel germline IGHV al...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Mikocziova, Ivana, Gidoni, Moriah, Lindeman, Ida, Peres, Ayelet, Snir, Omri, Yaari, Gur, Sollid, Ludvig M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261178/
https://ncbi.nlm.nih.gov/pubmed/32365177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa310
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