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Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions

Germline variations in immunoglobulin genes influence the repertoire of B cell receptors and antibodies, and such polymorphisms may impact disease susceptibility. However, the knowledge of the genomic variation of the immunoglobulin loci is scarce. Here, we report 25 potential novel germline IGHV al...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Mikocziova, Ivana, Gidoni, Moriah, Lindeman, Ida, Peres, Ayelet, Snir, Omri, Yaari, Gur, Sollid, Ludvig M
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261178/
https://ncbi.nlm.nih.gov/pubmed/32365177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa310
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