Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping

Analysis of antibody repertoires by high-throughput sequencing is of major importance in understanding adaptive immune responses. Our knowledge of variations in the genomic loci encoding immunoglobulin genes is incomplete, resulting in conflicting VDJ gene assignments and biased genotype and haploty...

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Publicado en:Nat Commun
Main Authors: Gidoni, Moriah, Snir, Omri, Peres, Ayelet, Polak, Pazit, Lindeman, Ida, Mikocziova, Ivana, Sarna, Vikas Kumar, Lundin, Knut E. A., Clouser, Christopher, Vigneault, Francois, Collins, Andrew M., Sollid, Ludvig M., Yaari, Gur
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367474/
https://ncbi.nlm.nih.gov/pubmed/30733445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08489-3
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