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Immunoglobulin germline gene variation and its impact on human disease

Immunoglobulins (Ig) play an important role in the immune system both when expressed as antigen receptors on the cell surface of B cells and as antibodies secreted into extracellular fluids. The advent of high-throughput sequencing methods has enabled the investigation of human Ig repertoires at unp...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Immun
Hauptverfasser: Mikocziova, Ivana, Greiff, Victor, Sollid, Ludvig M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234759/
https://ncbi.nlm.nih.gov/pubmed/34175903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41435-021-00145-5
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