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Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health
Female fertility and offspring health are critically dependent on an adequate supply of high-quality oocytes, the majority of which are maintained in the ovaries in a unique state of meiotic prophase arrest. While mechanisms of DNA repair during meiotic recombination are well characterized, the same...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260990/ https://ncbi.nlm.nih.gov/pubmed/32381741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001124117 |
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