Double-strand DNA breaks and repair response in human immature oocytes and their relevance to meiotic resumption

PURPOSE: Only 50–60 % of immature human oocytes attain the mature stage in vitro. Such a deficiency may be a reflection of inadequate conditions of in vitro maturation (IVM) or a manifestation of intrinsic oocyte defects. In the present study, we explored the possibility that the DNA of immature ooc...

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Библиографические подробности
Опубликовано в: :J Assist Reprod Genet
Главные авторы: Coticchio, Giovanni, Dal Canto, Mariabeatrice, Guglielmo, Maria Cristina, Albertini, David F., Mignini Renzini, Mario, Merola, Maria, Lain, Monia, Sottocornola, Manuela, De Ponti, Elena, Fadini, Rubens
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2015
Предметы:
Gamete Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615920/
https://ncbi.nlm.nih.gov/pubmed/26238391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-015-0547-6
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