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Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

The developmental potential of early embryos is mainly dictated by the quality of the oocyte. Here, we explore the utility of the maternal spindle transfer (MST) technique as a reproductive approach to enhance oocyte developmental competence. Our proof-of-concept experiments show that replacement of...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Costa-Borges, Nuno, Spath, Katharina, Miguel-Escalada, Irene, Mestres, Enric, Balmaseda, Rosa, Serafín, Anna, Garcia-Jiménez, Maria, Vanrell, Ivette, González, Jesús, Rink, Klaus, Wells, Dagan, Calderón, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259950/
https://ncbi.nlm.nih.gov/pubmed/32347793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48591
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