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Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

The developmental potential of early embryos is mainly dictated by the quality of the oocyte. Here, we explore the utility of the maternal spindle transfer (MST) technique as a reproductive approach to enhance oocyte developmental competence. Our proof-of-concept experiments show that replacement of...

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發表在:eLife
Main Authors: Costa-Borges, Nuno, Spath, Katharina, Miguel-Escalada, Irene, Mestres, Enric, Balmaseda, Rosa, Serafín, Anna, Garcia-Jiménez, Maria, Vanrell, Ivette, González, Jesús, Rink, Klaus, Wells, Dagan, Calderón, Gloria
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259950/
https://ncbi.nlm.nih.gov/pubmed/32347793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48591
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