Embryo developmental capability and pregnancy outcome are related to the mitochondrial DNA copy number and ooplasmic volume

PURPOSE: To investigate the correlation between the ooplasmic volume and the number of mitochondrial DNA (mtDNA) copies in embryos and how they may affect fecundity. METHOD: Using real-time PCR, mtDNA quantification was analyzed in unfertilized oocytes and uncleaved embryos. The size of the ovum was...

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Bibliographic Details
Main Authors: Murakoshi, Yukitaka, Sueoka, Kou, Takahashi, Kaori, Sato, Suguru, Sakurai, Tomoyoshi, Tajima, Hiroto, Yoshimura, Yasunori
Format: Artigo
Language:Inglês
Published: Springer US 2013
Subjects:
Embryo Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824848/
https://ncbi.nlm.nih.gov/pubmed/23897005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-013-0062-6
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