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Maternal spindle transfer overcomes embryo developmental arrest caused by ooplasmic defects in mice

The developmental potential of early embryos is mainly dictated by the quality of the oocyte. Here, we explore the utility of the maternal spindle transfer (MST) technique as a reproductive approach to enhance oocyte developmental competence. Our proof-of-concept experiments show that replacement of...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Costa-Borges, Nuno, Spath, Katharina, Miguel-Escalada, Irene, Mestres, Enric, Balmaseda, Rosa, Serafín, Anna, Garcia-Jiménez, Maria, Vanrell, Ivette, González, Jesús, Rink, Klaus, Wells, Dagan, Calderón, Gloria
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259950/
https://ncbi.nlm.nih.gov/pubmed/32347793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48591
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