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ProTAME Arrest in Mammalian Oocytes and Embryos Does Not Require Spindle Assembly Checkpoint Activity

In both mitosis and meiosis, metaphase to anaphase transition requires the activity of a ubiquitin ligase known as anaphase promoting complex/cyclosome (APC/C). The activation of APC/C in metaphase is under the control of the checkpoint mechanism, called the spindle assembly checkpoint (SAC), which...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Radonova, Lenka, Svobodova, Tereza, Skultety, Michal, Mrkva, Ondrej, Libichova, Lenka, Stein, Paula, Anger, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770151/
https://ncbi.nlm.nih.gov/pubmed/31540287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184537
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