The spindle assembly checkpoint is not essential for CSF arrest of mouse oocytes

In Xenopus oocytes, the spindle assembly checkpoint (SAC) kinase Bub1 is required for cytostatic factor (CSF)-induced metaphase arrest in meiosis II. To investigate whether matured mouse oocytes are kept in metaphase by a SAC-mediated inhibition of the anaphase-promoting complex/cyclosome (APC/C) co...

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Autors principals: Tsurumi, Chizuko, Hoffmann, Steffen, Geley, Stephan, Graeser, Ralph, Polanski, Zbigniew
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172623/
https://ncbi.nlm.nih.gov/pubmed/15611331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405165
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