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High-Fat Diet-Induced Obesity Modulates Colonic Lgr5 + Stem Cell Homeostasis by Dysregulating Plasma Membrane Organization

OBJECTIVES: The emerging obesity epidemic and its co-morbid conditions, such as colorectal cancer, pose a great challenge to global health and healthcare cost. This reinforces the urgent need to elucidate the underlying mechanisms contributing to the promotion of colon cancer in individuals with obe...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Salinas, Michael, Fuentes, Natividad, Wang, Xiaoli, Fan, Yang-Yi, Callaway, Evelyn, Landrock, Kerstin, McMurray, David, Chapkin, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259156/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa063_082
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