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Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5(+) colonic stem cells
Arachidonic acid (20:4(∆5,8,11,14), AA)-derived prostaglandin E(2) (PGE(2)) promotes colon cancer development. In contrast, chemoprotective n-3 polyunsaturated fatty acids supplant AA, thereby decreasing PGE(2) biosynthesis in colonocytes, with eicosapentaenoic acid (20:5(∆5,8,11,14,17), EPA) in par...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941743/ https://ncbi.nlm.nih.gov/pubmed/24336194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt412 |
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