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Alteration of colonic stem cell gene signatures during the regenerative response to injury

Since aberrant wound healing and chronic inflammation can promote malignant transformation, we determined whether dietary bioactive fish oil (FO)-derived n-3 polyunsaturated fatty acids (n-3 PUFA) modulate stem cell kinetics in a colitis-wounding model. Lgr5-LacZ and Lgr5-EGFP-IRES-creER(T2) mice we...

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Autors principals: Davidson, Laurie A., Goldsby, Jennifer S., Callaway, Evelyn S., Shah, Manasvi S., Barker, Nick, Chapkin, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418394/
https://ncbi.nlm.nih.gov/pubmed/22750333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.06.011
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