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Alteration of colonic stem cell gene signatures during the regenerative response to injury
Since aberrant wound healing and chronic inflammation can promote malignant transformation, we determined whether dietary bioactive fish oil (FO)-derived n-3 polyunsaturated fatty acids (n-3 PUFA) modulate stem cell kinetics in a colitis-wounding model. Lgr5-LacZ and Lgr5-EGFP-IRES-creER(T2) mice we...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418394/ https://ncbi.nlm.nih.gov/pubmed/22750333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.06.011 |
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