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Asaronic Acid Inhibited Glucose-Triggered M2-Phenotype Shift Through Disrupting the Formation of Coordinated Signaling of IL-4Rα-Tyk2-STAT6 and GLUT1-Akt-mTOR-AMPK
OBJECTIVES: Macrophage polarization has been implicated in the pathogenesis of metabolic diseases such as obesity, diabetes and atherosclerosis. Macrophages responsive to polarizing signals can result in their functional phenotype shifts. This study examined whether high glucose induced the function...
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| Publicado en: | Curr Dev Nutr |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7258294/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa052_035 |
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