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Asaronic Acid Inhibited Glucose-Triggered M2-Phenotype Shift Through Disrupting the Formation of Coordinated Signaling of IL-4Rα-Tyk2-STAT6 and GLUT1-Akt-mTOR-AMPK

Macrophage polarization has been implicated in the pathogenesis of metabolic diseases such as obesity, diabetes, and atherosclerosis. Macrophages responsiveness to polarizing signals can result in their functional phenotype shifts. This study examined whether high glucose induced the functional tran...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Oh, Hyeongjoo, Park, Sin-Hye, Kang, Min-Kyung, Kim, Yun-Ho, Lee, Eun-Jung, Kim, Dong Yeon, Kim, Soo-Il, Oh, Su Yeon, Na, Woojin, Lim, Soon Sung, Kang, Young-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400890/
https://ncbi.nlm.nih.gov/pubmed/32640667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12072006
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