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GLUT1 enhances mTOR activity independently of TSC2 and AMPK

Enhanced GLUT1 expression in mesangial cells plays an important role in the development of diabetic nephropathy by stimulating signaling through several pathways resulting in increased glomerular matrix accumulation. Similarly, enhanced mammalian target of rapamycin (mTOR) activation has been implic...

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Bibliographic Details
Main Authors: Buller, Carolyn L., Heilig, Charles W., Brosius, Frank C.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174561/
https://ncbi.nlm.nih.gov/pubmed/21613414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00472.2010
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