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GLUT1 enhances mTOR activity independently of TSC2 and AMPK

Enhanced GLUT1 expression in mesangial cells plays an important role in the development of diabetic nephropathy by stimulating signaling through several pathways resulting in increased glomerular matrix accumulation. Similarly, enhanced mammalian target of rapamycin (mTOR) activation has been implic...

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Autors principals: Buller, Carolyn L., Heilig, Charles W., Brosius, Frank C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174561/
https://ncbi.nlm.nih.gov/pubmed/21613414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00472.2010
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