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GLUT1 enhances mTOR activity independently of TSC2 and AMPK
Enhanced GLUT1 expression in mesangial cells plays an important role in the development of diabetic nephropathy by stimulating signaling through several pathways resulting in increased glomerular matrix accumulation. Similarly, enhanced mammalian target of rapamycin (mTOR) activation has been implic...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174561/ https://ncbi.nlm.nih.gov/pubmed/21613414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00472.2010 |
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