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GLUT1 enhances mTOR activity independently of TSC2 and AMPK

Enhanced GLUT1 expression in mesangial cells plays an important role in the development of diabetic nephropathy by stimulating signaling through several pathways resulting in increased glomerular matrix accumulation. Similarly, enhanced mammalian target of rapamycin (mTOR) activation has been implic...

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Bibliografske podrobnosti
Main Authors: Buller, Carolyn L., Heilig, Charles W., Brosius, Frank C.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174561/
https://ncbi.nlm.nih.gov/pubmed/21613414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00472.2010
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