Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Prevent Acidic pH-Induced Damage in Human Nucleus Pulposus Cells

BACKGROUND: The exosomes (Exo) derived from mesenchymal stem cells (MSCs) are capable of attenuating the apoptosis of nucleus pulposus cells (NPCs) elicited by proinflammatory cytokines. However, it remains unknown whether MSC-derived Exo also exert a protective effect on NPCs in the pathological ac...

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Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Li, Ming, Li, Ruoyu, Yang, Sidong, Yang, Dalong, Gao, Xianda, Sun, Jiayuan, Ding, Wenyuan, Ma, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2020
Schlagworte:
Lab/In Vitro Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257871/
https://ncbi.nlm.nih.gov/pubmed/32436493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.922928
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