Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

BACKGROUND: The stem cell-based therapies for intervertebral disc degeneration have been widely studied. However, the mechanisms of mesenchymal stem cells interacting with intervertebral disc cells, such as nucleus pulposus cells (NPCs), remain unknown. Exosomes as a vital paracrine mechanism in cel...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Lu, Kang, Li, Hai-yin, Yang, Kuang, Wu, Jun-long, Cai, Xiao-wei, Zhou, Yue, Li, Chang-qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424403/
https://ncbi.nlm.nih.gov/pubmed/28486958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0563-9
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