Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

BACKGROUND: The stem cell-based therapies for intervertebral disc degeneration have been widely studied. However, the mechanisms of mesenchymal stem cells interacting with intervertebral disc cells, such as nucleus pulposus cells (NPCs), remain unknown. Exosomes as a vital paracrine mechanism in cel...

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Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Lu, Kang, Li, Hai-yin, Yang, Kuang, Wu, Jun-long, Cai, Xiao-wei, Zhou, Yue, Li, Chang-qing
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424403/
https://ncbi.nlm.nih.gov/pubmed/28486958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0563-9
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