Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

BACKGROUND: The stem cell-based therapies for intervertebral disc degeneration have been widely studied. However, the mechanisms of mesenchymal stem cells interacting with intervertebral disc cells, such as nucleus pulposus cells (NPCs), remain unknown. Exosomes as a vital paracrine mechanism in cel...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Lu, Kang, Li, Hai-yin, Yang, Kuang, Wu, Jun-long, Cai, Xiao-wei, Zhou, Yue, Li, Chang-qing
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424403/
https://ncbi.nlm.nih.gov/pubmed/28486958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0563-9
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