Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration

Although mesenchymal stem cells (MSCs) transplantation into the IVD (intervertebral disc) may be beneficial in inhibiting apoptosis of nucleus pulposus cells (NPCs) and alleviating IVD degeneration, the underlying mechanism of this therapeutic process has not been fully explained. The purpose of thi...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Cheng, Xiaofei, Zhang, Guoying, Zhang, Liang, Hu, Ying, Zhang, Kai, Sun, Xiaojiang, Zhao, Changqing, Li, Hua, Li, Yan Michael, Zhao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742691/
https://ncbi.nlm.nih.gov/pubmed/28805297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13316
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