Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration

Although mesenchymal stem cells (MSCs) transplantation into the IVD (intervertebral disc) may be beneficial in inhibiting apoptosis of nucleus pulposus cells (NPCs) and alleviating IVD degeneration, the underlying mechanism of this therapeutic process has not been fully explained. The purpose of thi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Cheng, Xiaofei, Zhang, Guoying, Zhang, Liang, Hu, Ying, Zhang, Kai, Sun, Xiaojiang, Zhao, Changqing, Li, Hua, Li, Yan Michael, Zhao, Jie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742691/
https://ncbi.nlm.nih.gov/pubmed/28805297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13316
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