Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration

Although mesenchymal stem cells (MSCs) transplantation into the IVD (intervertebral disc) may be beneficial in inhibiting apoptosis of nucleus pulposus cells (NPCs) and alleviating IVD degeneration, the underlying mechanism of this therapeutic process has not been fully explained. The purpose of thi...

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Publicat a:J Cell Mol Med
Autors principals: Cheng, Xiaofei, Zhang, Guoying, Zhang, Liang, Hu, Ying, Zhang, Kai, Sun, Xiaojiang, Zhao, Changqing, Li, Hua, Li, Yan Michael, Zhao, Jie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742691/
https://ncbi.nlm.nih.gov/pubmed/28805297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13316
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