Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy

Degeneration of the cartilage endplate (CEP) induces intervertebral disc degeneration (IVDD). Nucleus pulposus cell (NPC) apoptosis is also an important exacerbating factor in IVDD, but the cascade mechanism in IVDD is not clear. We investigated the apoptosis of NPCs and IVDD when stimulated by norm...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cells
Autori principali: Luo, Liwen, Jian, Xiuying, Sun, Hui, Qin, Jinghao, Wang, Yanqiu, Zhang, Ji, Shen, Zigang, Yang, Di, Li, Changqing, Zhao, Ping, Liu, MingHan, Tian, Zhiqiang, Zhou, Yue
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2021
Soggetti:
Tissue‐specific Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8048856/
https://ncbi.nlm.nih.gov/pubmed/33459443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3322
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi