Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes

Stem cells derived from cartilage endplate (CEP) cells (CESCs) repair intervertebral disc (IVD) injury; however, the mechanism remains unclear. Here, we evaluated whether CESCs could transdifferentiate into nucleus pulposus cells (NPCs) via autocrine exosomes and subsequently inhibit IVD degeneratio...

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Gepubliceerd in:Front Cell Dev Biol
Hoofdauteurs: Luo, Liwen, Gong, Junfeng, Zhang, Hongyu, Qin, Jinghao, Li, Changqing, Zhang, Junfeng, Tang, Yu, Zhang, Yang, Chen, Jian, Zhou, Yue, Tian, Zhiqiang, Liu, Yao, Liu, MingHan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Cell and Developmental Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7970302/
https://ncbi.nlm.nih.gov/pubmed/33748142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.648201
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