Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats

Stem cell therapies for intervertebral disc degeneration have been demonstrated as a promising strategy. Previous studies have shown that human nucleus pulposus cell- (NPC-) derived exosomes can induce the differentiation of mesenchymal stem cells (MSCs) into NP-like cells in vitro. However, the mec...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Lan, Wei-ren, Pan, Sai, Li, Hai-yin, Sun, Chao, Chang, Xian, Lu, Kang, Jiang, Chang-qing, Zuo, Rui, Zhou, Yue, Li, Chang-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526523/
https://ncbi.nlm.nih.gov/pubmed/31249601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8404168
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