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Ethanol Augments Monosodium Urate-Induced NLRP3 Inflammasome Activation via Regulation of AhR and TXNIP in Human Macrophages

PURPOSE: Ethanol elicits several inflammatory responses and affects the innate immune response. The aim of this study was to identify the mechanism by which ethanol affects uric acid-induced NLR family pyrin domain-containing 3 (NLRP3) inflammasome activation by regulation of aryl hydrocarbon recept...

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Detalhes bibliográficos
Publicado no:Yonsei Med J
Main Authors: Kim, Seong-Kyu, Choe, Jung-Yoon, Park, Ki-Yeun
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255999/
https://ncbi.nlm.nih.gov/pubmed/32469177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2020.61.6.533
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