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Monosodium Urate in the Presence of RANKL Promotes Osteoclast Formation through Activation of c-Jun N-Terminal Kinase

The aim of this study was to clarify the role of monosodium urate (MSU) crystals in receptor activator of nuclear factor kB ligand- (RANKL-) RANK-induced osteoclast formation. RAW 264.7 murine macrophage cells were incubated with MSU crystals or RANKL and differentiated into osteoclast-like cells as...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Choe, Jung-Yoon, Park, Ki-Yeun, Kim, Seong-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549559/
https://ncbi.nlm.nih.gov/pubmed/26347587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/597512
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