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Melittin inhibits osteoclast formation through the downregulation of the RANKL-RANK signaling pathway and the inhibition of interleukin-1β in murine macrophages

Melittin is a major toxic component of bee venom (Apis mellifera). It is not known whether melittin is involved in bone metabolism and osteoclastogenesis. The aim of this study was to determine the role of melittin in the regulation of osteoclastogenesis. In vitro osteoclastogenesis assays were perf...

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Pubblicato in:Int J Mol Med
Autori principali: Choe, Jung-Yoon, Kim, Seong-Kyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360391/
https://ncbi.nlm.nih.gov/pubmed/28204822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2876
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