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Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures

The process of osteoclastic bone resorption is complex and regulated at multiple levels. The role of osteoclast (OCL) fusion and motility in bone resorption are unclear, with the movement of OCL on bone largely unexplored. RANKL (also known as TNFSF11) is a potent stimulator of murine osteoclastogen...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Fowler, Tristan W., Kamalakar, Archana, Akel, Nisreen S., Kurten, Richard C., Suva, Larry J., Gaddy, Dana
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327386/
https://ncbi.nlm.nih.gov/pubmed/25609708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.157834
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