Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures

The process of osteoclastic bone resorption is complex and regulated at multiple levels. The role of osteoclast (OCL) fusion and motility in bone resorption are unclear, with the movement of OCL on bone largely unexplored. RANKL (also known as TNFSF11) is a potent stimulator of murine osteoclastogen...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Fowler, Tristan W., Kamalakar, Archana, Akel, Nisreen S., Kurten, Richard C., Suva, Larry J., Gaddy, Dana
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327386/
https://ncbi.nlm.nih.gov/pubmed/25609708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.157834
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