Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis

Inflammasome-driven inflammation is postulated to play a role in multiple sclerosis (MS), but there is no direct evidence that the nod-like receptor protein 3 (NLRP3) inflammasome is involved in MS pathogenesis. Uric acid was shown to be one of the “danger” signals involved in the activation of NLRP...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Piancone, Federica, Saresella, Marina, Marventano, Ivana, La Rosa, Francesca, Santangelo, Maria Antonia, Caputo, Domenico, Mendozzi, Laura, Rovaris, Marco, Clerici, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945820/
https://ncbi.nlm.nih.gov/pubmed/29780394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00983
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