B Lymphocytes in Multiple Sclerosis: Bregs and BTLA/CD272 Expressing-CD19+ Lymphocytes Modulate Disease Severity

B lymphocytes contribute to the pathogenesis of Multiple Sclerosis (MS) by secreting antibodies and producing cytokines. This latter function was analyzed in myelin olygodendrocyte protein (MOG)-stimulated CD19+ B lymphocytes of 71 MS patients with different disease phenotypes and 40 age-and sex-mat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Piancone, Federica, Saresella, Marina, Marventano, Ivana, La Rosa, Francesca, Zoppis, Martina, Agostini, Simone, Longhi, Renato, Caputo, Domenico, Mendozzi, Laura, Rovaris, Marco, Clerici, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944189/
https://ncbi.nlm.nih.gov/pubmed/27412504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29699
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