Cyclooxygenase-2 haplotypes influence the longitudinal risk of malaria and severe malarial anemia in Kenyan children from a holoendemic transmission region

Cyclooxygenase-2 [(COX-2) or prostaglandin endoperoxide H2 synthase-2 (PTGS-2)] induces the production of prostaglandins as part of the host-immune response to infections. Although a number of studies have demonstrated the effects of COX-2 promoter variants on autoimmune and inflammatory diseases, t...

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Bibliographic Details
Published in:J Hum Genet
Main Authors: Anyona, Samuel B., Hengartner, Nicolas W., Raballah, Evans, Ong’echa, John Michael, Lauve, Nick, Cheng, Qiuying, Fenimore, Paul W., Ouma, Collins, Lambert, Christophe G., McMahon, Benjamin H., Perkins, Douglas J.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255056/
https://ncbi.nlm.nih.gov/pubmed/31664161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-019-0692-3
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