A TAZ-AXL-ABL2 feed-forward signaling axis promotes lung adenocarcinoma brain metastasis

Brain metastases are a common consequence of advanced lung cancer resulting in cranial neuropathies and increased mortality. Currently, there are no effective therapies to treat brain metastases due to a lack of actionable targets and failure of systemic therapies to penetrate the blood-brain barrie...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Hoj, Jacob P., Mayro, Benjamin, Pendergast, Ann Marie
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254883/
https://ncbi.nlm.nih.gov/pubmed/31825826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.018
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