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Role of the ABL tyrosine kinases in the epithelial–mesenchymal transition and the metastatic cascade

The ABL kinases, ABL1 and ABL2, promote tumor progression and metastasis in various solid tumors. Recent reports have shown that ABL kinases have increased expression and/or activity in solid tumors and that ABL inactivation impairs metastasis. The therapeutic effects of ABL inactivation are due in...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Luttman, Jillian Hattaway, Colemon, Ashley, Mayro, Benjamin, Pendergast, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140471/
https://ncbi.nlm.nih.gov/pubmed/34022881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-021-00739-6
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