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A TAZ-AXL-ABL2 feed-forward signaling axis promotes lung adenocarcinoma brain metastasis
Brain metastases are a common consequence of advanced lung cancer resulting in cranial neuropathies and increased mortality. Currently, there are no effective therapies to treat brain metastases due to a lack of actionable targets and failure of systemic therapies to penetrate the blood-brain barrie...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7254883/ https://ncbi.nlm.nih.gov/pubmed/31825826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.018 |
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