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Development of MAP4 kinase inhibitors as motor-neuron-protecting agents
Disease-causing mutations in many neurodegenerative disorders lead to proteinopathies that trigger endoplasmic reticulum (ER) stress. However, few therapeutic options exist for patients suffering from these diseases. Using an in vitro screening platform to identify compounds that protect human motor...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7253076/ https://ncbi.nlm.nih.gov/pubmed/31676236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.10.005 |
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